{
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  "Package": "Rsmlx",
  "Type": "Package",
  "Title": "R Speaks 'Monolix'",
  "Version": "2024.1.0",
  "Authors@R": "c(\nperson( \"Chloe\", \"Bracis\", role = c(\"ctb\",\"cre\"), email = \"support@lixoft.com\" ),\nperson( \"Frano\", \"Mihaljevic\", role = c(\"aut\") ),\nperson( \"Marc\", \"Lavielle\", role = c(\"aut\") ),\nperson( \"Jonathan\", \"Chauvin\", role = c(\"ctb\") ),\nperson( \"Clémence\", \"Pinaud\", role = c(\"ctb\")))",
  "Maintainer": "Chloe Bracis <support@lixoft.com>",
  "Description": "Provides methods for model building and model evaluation\nof mixed effects models using 'Monolix'\n<https://monolix.lixoft.com>. 'Monolix' is a software tool for\nnonlinear mixed effects modeling that must have been installed\nin order to use 'Rsmlx'. Among other tasks, 'Rsmlx' provides a\npowerful tool for automatic PK model building, performs\nstatistical tests for model assessment, bootstrap simulation\nand likelihood profiling for computing confidence intervals.\n'Rsmlx' also proposes several automatic covariate search\nmethods for mixed effects models.",
  "URL": "https://monolix.lixoft.com/rsmlx/",
  "SystemRequirements": "'Monolix' (<https://monolix.lixoft.com>)",
  "Collate": "mlxConnectors.R bootstrap.R buildmlx.R buildVar.R buildAll.R\nconfintmlx.R correlationModelSelection.R\ncovariateModelSelection.R covariateSearch.R\nerrorModelSelection.R llp.R newConnectors.R setSettings.R\ntestmlx.R zzz.R RsmlxTools.R readDatamlx.R pkbuild.R pkpopini.R\nwhichPKmodel.R",
  "License": "BSD_2_clause + file LICENSE",
  "Copyright": "Inria",
  "NeedsCompilation": "no",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "7.3.1",
  "Config/pak/sysreqs": "libicu-dev",
  "Repository": "https://marclavielle.r-universe.dev",
  "Date/Publication": "2024-06-10 13:23:28 UTC",
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  "RemoteRef": "HEAD",
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  "Packaged": {
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    "User": "root"
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    "message": "More changes for CRAN submission (remove links to lixoftConnectors in help)\n",
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      "date": "2019-04-30"
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    "buildAll",
    "buildmlx",
    "buildVar",
    "confintmlx",
    "covariateSearch",
    "getEstimatedCovarianceMatrix",
    "getEstimatedIndividualParameters2",
    "getEstimatedPredictions",
    "getEstimatedResiduals",
    "getSimulatedPredictions",
    "getSimulatedResiduals",
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    "readDatamlx",
    "setSettings",
    "testmlx",
    "whichPKmodel"
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      "title": "Monolix results",
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      ],
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      "table": false,
      "tojson": true
    },
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      "title": "Monolix project for warfarin PK - 1",
      "object": "RsmlxDemo",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "RsmlxDemo2.project",
      "title": "Monolix project for warfarin PK - 2",
      "object": "RsmlxDemo",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "warfarin.data",
      "title": "warfarin PKPD data",
      "object": "RsmlxDemo",
      "class": [
        "data.frame"
      ],
      "fields": [
        "id",
        "time",
        "amt",
        "dv",
        "dvid",
        "wt",
        "sex",
        "age"
      ],
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      "table": true,
      "tojson": true
    }
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      "title": "Bootstrapping - case resampling",
      "topics": [
        "bootmlx"
      ]
    },
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      "topics": [
        "buildAll"
      ]
    },
    {
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      "title": "Automatic statistical model building",
      "topics": [
        "buildmlx"
      ]
    },
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      "topics": [
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      ]
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      "title": "Confidence intervals for population parameters",
      "topics": [
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      "title": "Covariate model building",
      "topics": [
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    {
      "page": "getEstimatedCovarianceMatrix",
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      "topics": [
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      ]
    },
    {
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      "topics": [
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    },
    {
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      "title": "Get estimated predictions",
      "topics": [
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      ]
    },
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      "page": "getEstimatedResiduals",
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      "topics": [
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    },
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      "topics": [
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      ]
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      "title": "Automatic PK model building",
      "topics": [
        "pkbuild"
      ]
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      "topics": [
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        "resMonolix"
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    },
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